Titanium dioxide nanoparticles as a promising tool for efficient separation of trace DNA via phosphate-mediated desorption

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成果类型：

期刊论文

作者：

Li, Song;Tang, Jing;Bai, Yalong;Pu, Chunmin;Liao, Xiaoyan;...

通讯作者：

Chen, LL;Bai, YL

作者机构：

[Li, Song; Pu, Chunmin; Tang, Jing; Chen, Lili; Liao, Xiaoyan] Univ South China, Coll Publ Hlth, Hengyang Med Sch, Dept Publ Hlth Lab Sci, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

[Li, Song; Pu, Chunmin; Tang, Jing; Bai, Yalong; Liao, Xiaoyan] Shanghai Acad Agr Sci, Inst Agrifood Stand & Testing Technol, 1000 Jinqi Rd, Shanghai 201403, Peoples R China.

通讯机构：

[Chen, LL ] U

[Bai, YL ] S

Univ South China, Coll Publ Hlth, Hengyang Med Sch, Dept Publ Hlth Lab Sci, 28 Changsheng West Rd, Hengyang 421001, Hunan, Peoples R China.

Shanghai Acad Agr Sci, Inst Agrifood Stand & Testing Technol, 1000 Jinqi Rd, Shanghai 201403, Peoples R China.

语种：

英文

关键词：

DNA extraction;DNAdesorption;TiO2 nanoparticles

期刊：

Microchimica Acta

ISSN：

0026-3672

年：

2025

卷：

192

期：

页码：

1-10

DOI：

10.1007/s00604-025-07511-4

基金类别：

This research was supported by the Shanghai Academy of Agricultural Sciences Applied Basic Research, China (Grant No. 2025–09).

机构署名：

本校为第一且通讯机构

院系归属：

公共卫生学院

摘要：

We systematically evaluated the DNA adsorption and desorption efficiencies of several nanoparticles. Among them, titanium dioxide (TiO₂) nanoparticles (NPs), aluminum oxide (Al₂O₃) NPs, and zinc oxide (ZnO) NPs exhibited strong DNA-binding capacities under mild conditions. However, phosphate-mediated DNA displacement efficiencies varied considerably, with only TiO₂ NPs showing consistently superior performance. Further investigation into the DNA adsorption and desorption mechanisms of TiO₂ NPs led to the following key results: (1) TiO₂ NP...

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Titanium dioxide nanoparticles as a promising tool for efficient separation of trace DNA via phosphate-mediated desorption

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