In the system reliability and safety assessment, the focuses are not only the risks caused by hardware or software, but also the risks caused by “human error”. There are uncertainties in the traditional human error risk assessment (e.g. HECA) due to the uncertainties and imprecisions in Human Error Probability (HEP), Error-Effect Probability (EEP) and Error Consequence Severity (ECS). While fuzzy logic can deal with uncertainty and imprecision. It is an efficient tool for solving problems where knowledge uncertainty may occur. The purpose of this paper is to develop a new Fuzzy Human Error Risk Assessment Methodology (FHERAM) for determining Human Error Risk Importance (HERI) as a function of HEP, EEP and ECS. The modeling technique is based on the concept of fuzzy logic, which offers a convenient way of representing the relationships between the inputs (i.e. HEP, EEP, and ECS) and outputs (i.e. HERI) of a risk assessment system in the form of IF–THEN rules. It is implemented on fuzzy logic toolbox of MATLAB using Mamdani techniques. A case example is presented to demonstrate the proposed approach. Results show that the method is more realistic than the traditional ones, and it is practicable and valuable.