Nantong Science and Technology Bureau [MS22015105, MS3201605]; Natural Science Foundation of Jiangsu ProvinceNatural Science Foundation of Jiangsu Province [BK20160420]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81600449]; National Natural Science Foundation of Young Scientists of ChinaNational Natural Science Foundation of China (NSFC) [81602443]; Health Bureau of Nantong City [WQ2016011]
机构署名：
本校为其他机构
院系归属：
医学院
摘要：
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide. Thyroid hormone receptor interactor 13 (TRIP13) has been reported to promote nonhomologous end joining (NHEJ). However, the role of TRIP13 in the molecular pathogenesis of HCC remains to be elucidated. The aim of the present study was to investigate the role and potential mechanism of TRIP13 in HCC. Real-time PCR and western blotting were used to detect the expression of TRIP13 in 47 paired HCC and adjacent liver tissues. The Cancer Genome Atlas (TCGA) database was used to collect TRIP13 expressio...
