National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81172575]
机构署名：
本校为第一且通讯机构
院系归属：
医学院
摘要：
Understanding the molecular mechanisms underlying gastric cancer progression contributes to the development of novel targeted therapies. In this study, we found that the expression levels of miR-125b were strongly downregulated in gastric cancer and associated with clinical stage and the presence of lymph node metastases. Additionally, miR-125b could independently predict OS and DFS in gastric cancer. We further found that upregulation of miR-125b inhibited the proliferation and metastasis of gastric cancer cells in vitro and in vivo. miR-125b ...
