This paper presents a hybrid differential evolution (DE) with quantum-behaved particle swarm optimization (QPSO) for the unmanned aerial vehicle (UAV) route planning on the sea. The proposed method, denoted as DEQPSO, combines the DE algorithm with the QPSO algorithm in an attempt to further enhance the performance of both algorithms. The route planning for UAV on the sea is formulated as an optimization problem. A simple method of pretreatment to the terrain environment is proposed. A novel route planner for UAV is designed to generate a safe and flyable path in the presence of different thre...