Insights into the fluoride-resistant regulation mechanism of Acidithiobacillus ferrooxidans ATCC 23270 based on whole genome microarrays

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成果类型：

期刊论文

作者：

Ma, Liyuan;Li, Qian;Shen, Li;Feng, Xue;Xiao, Yunhua;...

通讯作者：

Liu, Xueduan

作者机构：

[Feng, Xue; Yin, Huaqun; Liu, Xueduan; Xiao, Yunhua; Liang, Yili; Shen, Li; Ma, Liyuan; Tao, Jiemeng] Cent S Univ, Sch Minerals Proc & Bioengn, Changsha 410083, Hunan, Peoples R China.

[Feng, Xue; Yin, Huaqun; Liu, Xueduan; Xiao, Yunhua; Liang, Yili; Shen, Li; Ma, Liyuan; Tao, Jiemeng] Minist Educ, Key Lab Biomet, Changsha, Hunan, Peoples R China.

[Li, Qian] Univ South China, Sch Nucl Resources Engn, Hengyang, Peoples R China.

[Li, Qian] Univ South China, Key Discipline Lab Natl Def Biotechnol Uranium Mi, Hengyang, Peoples R China.

通讯机构：

[Liu, Xueduan] C

[Liu, Xueduan] M

Cent S Univ, Sch Minerals Proc & Bioengn, Changsha 410083, Hunan, Peoples R China.

Minist Educ, Key Lab Biomet, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

Fluoride;A. ferrooxidans ATCC 23270;Whole genome microarray;Expression profiling

期刊：

Journal of Industrial Microbiology & Biotechnology

ISSN：

1367-5435

年：

2016

卷：

期：

页码：

1441-1453

DOI：

10.1007/s10295-016-1827-6

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [NSFC 31570113]; Fundamental Research Funds for the Central Universities of Central South University [2016zzts110]

机构署名：

本校为其他机构

院系归属：

核资源工程学院

摘要：

Acidophilic microorganisms involved in uranium bioleaching are usually suppressed by dissolved fluoride ions, eventually leading to reduced leaching efficiency. However, little is known about the regulation mechanisms of microbial resistance to fluoride. In this study, the resistance of Acidithiobacillus ferrooxidans ATCC 23270 to fluoride was investigated by detecting bacterial growth fluctuations and ferrous or sulfur oxidation. To explore the regulation mechanism, a whole genome microarray was used to profile the genome-wide expression. The fluoride tolerance of A. ferrooxidans cultured in ...

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Insights into the fluoride-resistant regulation mechanism of Acidithiobacillus ferrooxidans ATCC 23270 based on whole genome microarrays

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