版权说明 操作指南
首页 > 成果 > 详情

Lipoprotein lipase: Biosynthesis, regulatory factors, and its role in atherosclerosis and other diseases

认领
导出
下载 Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
He, Ping-Ping;Jiang, Ting;OuYang, Xin-Ping;Liang, Ya-Qin;Zou, Jie-Qiong;...
通讯作者:
Liao, Li;Zheng, Xi-Long
作者机构:
[OuYang, Xin-Ping; He, Ping-Ping] Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, 28 West Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.
[Liao, Li; He, Ping-Ping; Liang, Ya-Qin; Zou, Jie-Qiong; Shen, Qian-Qian; Wang, Yan] Univ South China, Sch Nursing, Hengyang 421001, Hunan, Peoples R China.
[Jiang, Ting] Guilin Med Univ, Off Acad Affairs, Dept Practice Educ, Guilin 541004, Guangxi, Peoples R China.
[OuYang, Xin-Ping] Univ South China, Coll Med, Neurosci Inst, Dept Physiol, Hengyang 421001, Hunan, Peoples R China.
[Zou, Jie-Qiong; Wang, Yan] Affiliated First Hosp, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Liao, Li; Zheng, Xi-Long] U
Univ South China, Sch Nursing, Hengyang 421001, Hunan, Peoples R China.
Univ Calgary, Cumming Sch Med, Libin Cardiovasc Inst Alberta, Dept Biochem & Mol Biol,Hlth Sci Ctr, 3330 Hosp Dr NW, Calgary, AB T2N 4N1, Canada.
语种:
英文
关键词:
Atherosclerosis;LPL;Lipoprotein;Macrophages;Triglyceride
期刊:
Clinica Chimica Acta
ISSN:
0009-8981
年:
2018
卷:
480
页码:
126-137
基金类别:
The authors gratefully acknowledge the financial supports from Canadian Institutes of Health Research (CIHR MOP-119511 to X.-L.Z.), the National Natural Sciences Foundation of China (81300158), Aid Program for Science and Technology Department of Human Province (2015JC3083), Hunan province graduate student scientific research innovation project (CX2014B393, CX2016B485), Scientific Research Aid Program for Chinese Medicine of Human Province (201524), the financial support from Zhengxiang Scholar Program of University of South China (2014-004), The start-up funds for Ph.Ds in University of South China (2014XQD36, 2015XQD37), Graduate student innovation project of Cooperative innovation Center for Molecular Target New Drug (0223-0002-D0033), High Level Talents Aid Program in University of South China (2017-28) and Major project of Nursing School of University of South China (HLPY006).
机构署名:
本校为通讯机构
院系归属:
医学院
护理学院
摘要:
Lipoprotein lipase (LPL) is a rate-limiting enzyme that catalyzes hydrolysis of the triglyceride (TG) core of circulating TG-rich lipoproteins including chylomicrons (CM), low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL). A variety of parenchymal cells can synthesize and secrete LPL. Recent studies have demonstrated that complicated processes are involved in LPL biosynthesis, secretion and transport. The enzyme activity of LPL is regulated by many factors, such as apolipoproteins, angiopoietins, hormones and miRNAs. In th...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com