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LncRNAs: key players and novel insights into cervical cancer

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成果类型:
期刊论文
作者:
Peng, Li;Yuan, Xiaoqing;Jiang, Binyuan;Tang, Zaili;Li, Guan-Cheng*
通讯作者:
Li, Guan-Cheng
作者机构:
[Jiang, Binyuan; Peng, Li; Li, Guan-Cheng] Cent S Univ, Canc Res Inst, Changsha 410078, Hunan, Peoples R China.
[Jiang, Binyuan; Peng, Li; Li, Guan-Cheng] Natl Hlth & Family Planning Commiss, Key Lab Carcinogenesis, Changsha 410078, Hunan, Peoples R China.
[Jiang, Binyuan; Peng, Li; Li, Guan-Cheng] Minist Educ, Key Lab Carcinogenesis & Canc Invas, Changsha 410078, Hunan, Peoples R China.
[Yuan, Xiaoqing] Cent S Univ, Xiangya Hosp, Dept Clin Pharmacol, Changsha 410008, Hunan, Peoples R China.
[Yuan, Xiaoqing] Cent S Univ, Inst Clin Pharmacol, Hunan Key Lab Pharmacogenet, Changsha 410078, Hunan, Peoples R China.
通讯机构:
[Li, Guan-Cheng] C
[Li, Guan-Cheng] N
[Li, Guan-Cheng] M
Cent S Univ, Canc Res Inst, Changsha 410078, Hunan, Peoples R China.
Natl Hlth & Family Planning Commiss, Key Lab Carcinogenesis, Changsha 410078, Hunan, Peoples R China.
语种:
英文
关键词:
Cervical cancer;Dysregulation;EMT;EZH2;Function;GAS5;HOTAIR;LncRNA;LncRNA-ANRIL;LncRNA-CCHE1;LncRNA-EBIC;LncRNA-LET;MALAT1;MEG3;Mechanism;NEAT2;TUSC8;Xist;ceRNA;m6A
期刊:
Tumor Biology
ISSN:
1010-4283
年:
2016
卷:
37
期:
3
页码:
2779-2788
基金类别:
Fundamental Research Funds for the Central Universities of Central South University [2015zzts096]; Science and Technology Department Research Foundation of Hunan province [12JJ2052]; Open-End Fund for the Valuable and Precision Instruments of Central South University [CSU2C2013048]
机构署名:
本校为其他机构
摘要:
Cervical cancer contributed the second highest number of deaths in female cancers, exceeded only by breast cancer, carrying high risks of morbidity and mortality. There was a great need and urgency in searching novel treatment targets and prognosis biomarkers to improve the survival rate of cervical cancer patients. Many long non-coding RNAs (lncRNAs) were emerging as pivotal regulators in various biological processes and took vitally an effect on the oncogenesis and progression of cervical cancer. In this review, we summarized the origin and overview function of lncRNAs; highlighted the roles...

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