miR-200b and miR-200c as Prognostic Factors and Mediators of Gastric Cancer Cell Progression

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tang, Hailin;Deng, Min;Tang, Yunyun;Xie, Xinhua;Guo, Jiaoli;...

通讯作者：

Xie, Xiaoming

作者机构：

[Tang, Hailin; Xie, Xinhua; Xie, Xiaoming; Kong, Yanan; Guo, Jiaoli; Ye, Feng] Sun Yat Sen Univ, Dept Breast Oncol, Ctr Canc, Guangzhou 510060, Guangdong, Peoples R China.

[Tang, Hailin; Xie, Xinhua; Xie, Xiaoming; Kong, Yanan; Guo, Jiaoli; Ye, Feng] Sun Yat Sen Univ, Ctr Canc, State Key Lab Oncol South China, Guangzhou 510060, Guangdong, Peoples R China.

[Deng, Min] Guangzhou Med Univ, Canc Hosp, Guangzhou, Guangdong, Peoples R China.

[Deng, Min] Guangzhou Med Univ, Canc Res Inst, Guangzhou, Guangdong, Peoples R China.

[Tang, Hailin; Tang, Yunyun; Deng, Min; Su, Qi] Univ South China, Canc Res Inst, Hengyang, Hunan, Peoples R China.

通讯机构：

[Xie, Xiaoming] S

Sun Yat Sen Univ, Dept Breast Oncol, State Key Lab Oncol South China, Ctr Canc, 651 East Dongfeng Rd, Guangzhou 510060, Guangdong, Peoples R China.

语种：

英文

期刊：

Clinical Cancer Research

ISSN：

1078-0432

年：

2013

卷：

期：

页码：

5602-5612

DOI：

10.1158/1078-0432.CCR-13-1326

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31100935, 81272514]; Key Program of National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31030061]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2012M520075]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Purpose: The purpose of this study was to investigate the clinicopathologic significance and potential role of miR-200b and miR-200c in the development and progression of gastric cancer. Experimental Design: We examined miR-200b and miR-200c expression in 36 paired normal and stomach tumor specimens, as well as gastric cancer cell lines, by quantitative real-time PCR. In addition, miR-200b and miR-200c were detected by ISH using gastric cancer tissue microarrays, and the association between miR-200b and miR-200c levels and clinicopathologic fac...

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miR-200b and miR-200c as Prognostic Factors and Mediators of Gastric Cancer Cell Progression

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