The Interaction of Serum Proteins with Carbon Nanotubes Depend on the Physicochemical Properties of Nanotubes

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成果类型：

期刊论文

作者：

Du, Jiangfeng;Ge, Cuicui;Lu, Ying;Bai, Ru;Li, Denghua;...

通讯作者：

Liao, Lifu

作者机构：

[Du, Jiangfeng; Liao, Lifu] Univ S China, Coll Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.

[Lu, Ying; Yang, Yanlian; Du, Jiangfeng; Li, Denghua; Chen, Chunying; Bai, Ru; Ge, Cuicui] Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China.

[Lu, Ying; Yang, Yanlian; Du, Jiangfeng; Li, Denghua; Chen, Chunying; Bai, Ru; Ge, Cuicui] Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China.

通讯机构：

[Liao, Lifu] U

Univ S China, Coll Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Carbon Nanotubes;Fetal Bovine Serum;CNT-Protein Interaction;Peg Modification;Gel Electrophoresis;Mass Spectrometry;Atomic Force Microscope

期刊：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

ISSN：

1533-4880

年：

2011

卷：

期：

页码：

10102-10110

DOI：

10.1166/jnn.2011.4976

基金类别：

Ministry of Science and Technology of ChinaMinistry of Science and Technology, China [2011CB933401, 2010CB934004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [10975040]; CASChinese Academy of Sciences

机构署名：

本校为第一且通讯机构

院系归属：

化学化工学院

摘要：

With more and more potential applications of carbon nanotubes (CNTs) in different fields, the risk of exposure to CNTs is increasing. The interaction between CNTs and protein in biological media can affect the way cells interact with, recognize and process the nanoparticles, and this has important implications for safety considerations. In this study, the interaction of single-walled and multiwall CNTs with various serum proteins was investigated. The adsorption kinetics of protein to CNTs was investigated and a semi-qualitative analysis was provided by sodium dodecyl sulfate polyacrylamide ge...

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The Interaction of Serum Proteins with Carbon Nanotubes Depend on the Physicochemical Properties of Nanotubes

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