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Reduction of CAII Expression in Gastric Cancer: Correlation withInvasion and Metastasis

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成果类型:
期刊论文
作者:
Li, Xiao-jie;Xie, Hai-long*;Lei, San-ju;Cao, Hui-qiu;Meng, Tian-Yun;...
通讯作者:
Xie, Hai-long
作者机构:
[Meng, Tian-Yun; Cao, Hui-qiu; Li, Xiao-jie; Hu, Yu-lin] 1st Peoples Hosp Chenzhou, Dept Pathol, Chenzhou 423000, Peoples R China.
[Xie, Hai-long; Li, Xiao-jie] Univ S China, Inst Canc Res, Hengyang 421001, Peoples R China.
[Lei, San-ju] 1st Peoples Hosp Chenzhou, Dept Otorhinolaryngol, Chenzhou 423000, Peoples R China.
通讯机构:
[Xie, Hai-long] U
Univ S China, Inst Canc Res, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
CAII;Gastric Carcinoma;Immunohistochemistry;Invasion;Metastasis
关键词(中文):
肿瘤侵袭;胃癌;免疫组织化学;黏膜上皮;阳性率;淋巴结;病理特征;技术检测
期刊:
中国癌症研究:英文版
ISSN:
1000-9604
年:
2012
卷:
24
期:
3
页码:
196-200
基金类别:
This work was supported by the National Natural Science Foundation of China (No.81172576) and by a grant from Technology Division of Chenzhou, China (No. 2008gl15). *Corresponding author. E-mail: xhl0078@sina.com.cn
机构署名:
本校为通讯机构
院系归属:
医学院
摘要:
Objective: Human carbonic anhydrases II (CAII) gene plays an important role in different cancer. However, its relevance to gastric cancer (GC) remains unclear. In the present study, we aimed to investigate the expression of CAII in GC and explore its correlation with some clinicopathologic characteristics of GC. Methods: The expression of CAII in 20 specimens of normal gastric mucosa, 38 specimens of intraepithelial neoplasia and 112 specimens of gastric carcinoma were detected by immunohistochemical techniques. Survival in GC with CAII express...
摘要(中文):
客观人的碳的 anhydrases II (CAII ) 基因在不同癌症起一个重要作用。然而,它到胃的癌症(GC ) 的关联仍然保持不清楚。在现在的学习,我们试图在 GC 调查 CAII 的表示并且与 GC 的一些 clinicopathologic 特征探索它的关联。

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